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TSQ Altis Plus Mass Spectrometer

Very high reliability of detection and quantitative analysis of targeted compounds through ultra-high sensitivity

Key words:

  • Commodity name： TSQ Altis Plus Mass Spectrometer

Category:

Triple quadrupole LC-MS

E-mail:

zhuohuangkeji@163.com

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  • Product Description

  • Product advantages

    Very high reliability of detection and quantitative analysis of targeted compounds through ultra-high sensitivity

    Over 6 orders of magnitude linear dynamic range with high selectivity. The enhanced acquisition speed has driven large-scale research in the development and optimization of ion-pair methods, with effective residence times as low as 0.3 milliseconds, while the polarity switching time of 5 milliseconds can increase the flux in fewer experiments.

    The instrumental capabilities of the TSQ Altis Plus triple quadrupole mass spectrometer accelerate high-performance targeted experiments on complex matrices when data must be reliable.

    Explore higher levels of productivity with the TSQ Plus mass spectrometer portfolio

    High-throughput screening and quantitative analysis

    The innovative technology of ion source, mass analyzer, active Q2 collision cell and RF electronics provides high sensitivity, high selectivity and acquisition speed/polarity switching time, which is very suitable for ultra-high performance liquid chromatography (UHPLC) separation. With preset SRM ion tables and acquisition rates of up to 600 SRM/sec, each method can screen or quantitatively analyze thousands of compounds. In challenging matrices, rapid data acquisition at very low concentrations results in the number of data points needed to achieve high confidence.

    Extended experimental functionality

    The integrated workflow solution is centered on the TSQ Altis Plus mass spectrometer to meet regulatory requirements for a growing variety of compound catalogues. New UHPLC and ion chromatography (IC) systems can greatly improve sample transport and separation capabilities, maintaining their sensitivity to meet very low residual margins without the use of expensive sample preparation or derivatization steps. Thermo Scientific Chromeleon Chromatography Data System (CDS) software to control all experimental attributes in a regulatory environment to further increase productivity.

    Simple operation

    Targeted research and routine applications require fast-response instrument control software that is intuitive to operate. The simplified calibration method integrates the steps required by the operator, as well as intelligent instrument check and calibration procedures. The TSQ mass spectrometer direct transfer method Scientific previous generation Thermo maintains or improves performance without the need for optimization.

    The dwell time assigned to each ion pair transition is automatically determined in the experiment based on the user-defined chromatographic peak width and fixed cycle time options or the number of data points per chromatographic peak. The priority setting allows further adjustment.

    database integration

    The development of targeted harvesting methods requires optimized product ions and collision energies. Utilizing libraries of experiments created from discovery experiments can eliminate the need to purify standards and long optimization procedures. The output of processed data in the Thermo Scientific TraceFinder software can be imported directly into the instrument method editor, simplifying the creation of a large number of ion pair methods.

    However, discovery experiments may not include all compounds targeted for study. Integration with the Thermo Scientific mzCloud database makes it possible to select additional compounds from the advanced mass spectrometry database that will be added to existing experimental methods.

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